Abstract: This study is the product of a base line study (human resource development study in science, technology and innovation) launched by Innovation Partnership Programme (IPP) (An ODA program jointly financed by Governments Finland and Vietnam, since 2009). The research aims at presenting an empirical study of human resource capacity building for innovation through doing survey, fieldwork and face-to-face interviews with business leaders and managers of Vietnamese enterprises in 2012. The enterprises participated in the survey are the members of Young Entrepreneurs Associations. The fieldwork has been conducted between March and June in six locations in Vietnam which are Ha Noi, Hai Phong, Da Nang, Da Lat, An Giang and Ho Chi Minh City. The information collected in the survey includes background of the respondents, status of innovation work in the enterprise and the opinions on human resource capacity of 583 Vietnamese enterprises. We expect the results can support enterprises, public management agencies, research organizations, universities and individuals to have better capacity in the innovative activities.