Authors : HasnorIzzati Che Razali, Ismail Zainol, Wan Rusmawati Wan Mahamod, Haniza Hanim Mat Zain, Norlaili Abu Bakar, Mohd Anuar Alwi and Norlizah Jamil
Abstract: Hydrolysed collagen intake has been shown to have a positive effect on flexibility and elasticity of the skin. However, topical use of hydrolysed collagen in emulsion form is under-explored. The aim of this study was to investigate the effect of hydrolysed collagen existence on the physical stability and droplet size of different formulations of water-in-virgin coconut oil emulsion. The obtained emulsion via. high shear homogenization, both before and after incorporated with hydrolysed collagen showed good physical stability with no separation layersand suitable to be administered on skin. Incorporating hydrolysed collagen caused a small additional decrease in emulsion droplet size compared to typical emulsion. The dispersion of small water-based hydrolysed collagen droplets in emulsion plays an important role for a better permeation of hydrolysed collagen into the skin, once it applied topically. The rheological properties of emulsion attribute to shear thinning behaviour which is appropriate for the needs in the topical application. The results recommend an emulsion system as an innovative approach for enhancing the transdermal penetration of hydrolysed collagen into skin for topical application.
HasnorIzzati Che Razali, Ismail Zainol, Wan Rusmawati Wan Mahamod, Haniza Hanim Mat Zain, Norlaili Abu Bakar, Mohd Anuar Alwi and Norlizah Jamil, 2019. Effect of Fish Scale Hydrolysed Collagen on Stability of Water-in-Virgin Coconut Oil Emulsion for Potential Topical Application. Journal of Engineering and Applied Sciences, 14: 7647-7655.