Authors : Farnaz Sepasi , Azin Alizadeh Asl and Rasoul Azarfarin
Abstract: Different risk factors affect development of atherosclerosis and Coronary Artery Disease (CAD). These factors are believed to be of value in prediction and prevention of coronary events. Here in we report the relation between blood groups, cardiovascular risk factors and Myocardial Infarction incidence. Measurements were made in samples obtained from 500 patients who had admitted to Cardiac Care Unit (CCU) of Madani heart center of Tabriz, Iran due to first Acute Myocardial Infarction (AMI) from Jan 2005 to April 2007. Participants provided blood samples for Cholesterol, Glucose (Fasting Blood Sugar (FBS)), Cardiac enzymes and Blood Groups (BG). Standard 12-lead electrocardiograms were obtained immediately after admission. Patients were also asked about current smoking history, Hypertension (HTN) and Diabetes Mellitus (DM) history. Analysis showed significant differences between the frequency of ABO blood groups and AMI, Smoking, Serum Cholesterol, but non significant relation with HTN, DM and the location of MI. In individuals the incidence of AMI was higher in those with BG A; while, sleeping MI was higher in group O. AMI was less frequent in BG AB. The mean serum cholesterol level and positive current smoking history were significantly higher in AMI patients with BG A. Blood group A is related to the higher incidence of AMI, hypercholesterolemia and positive current smoking history, but the findings don�t support the view that ABO blood groups and AMI are related to HTN, DM and location of MI.
Farnaz Sepasi , Azin Alizadeh Asl and Rasoul Azarfarin , 2008. Relation Between ABO Blood Groups, Cardiovascular Risk Factors and Acute Myocardial Infarction. Research Journal of Biological Sciences, 3: 1060-1062.