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Research Journal of Biological Sciences
Year: 2010 | Volume: 5 | Issue: 10 | Page No.: 647-649
DOI: 10.3923/rjbsci.2010.647.649  
Evaluation of Hypoglycemic and Antioxidative Properties of Aqueous Extract of Garcinia kola Seeds in Wistar Rats
Omage Kingsley , Idokpesi O. Georginah , Josiah J. Sunday , Uhunmwangho S. Eseosa and Ajeigbe O. Kazeem
 
Abstract: The effects of aqueous extract of Garcinia kola seed on glucose, superoxide dismutase catalase and malondialdehyde of normal rats were investigated. Oral administration of aqueous seed extract of Garcinia kola at a concentration of 200 mg kg-1 body weight over a period of 21 days, significantly (p<0.05) decreased the levels of blood glucose, increased the activity of superoxide dismutase (p<0.05) and that of malondialdehyde (p<0.05). The treatment however had no significant effect (p>0.05) on the activity of catalase. The elicitation of these effects by the plant is a reflection of its hypoglycemic and antioxidative properties.
 
How to cite this article:
Omage Kingsley, Idokpesi O. Georginah, Josiah J. Sunday, Uhunmwangho S. Eseosa and Ajeigbe O. Kazeem, 2010. Evaluation of Hypoglycemic and Antioxidative Properties of Aqueous Extract of Garcinia kola Seeds in Wistar Rats. Research Journal of Biological Sciences, 5: 647-649.
DOI: 10.3923/rjbsci.2010.647.649
URL: http://medwelljournals.com/abstract/?doi=rjbsci.2010.647.649