Authors : Aliza Zeidman , Gideon Y. Stein , Kanter Pazit , Amos H. Cohen , Fradin Zinaida and Edward Ram
Abstract: Modalities of treatment in Primary Gastric Lymphoma (PGL) are still controversial. The purpose of this study is to seek the better treatment modality in terms of survival. Charts of patients diagnosed with PGL, between 1980-2003, were reviewed and divided into 2 groups by modality of treatment: Group A included patients treated by surgery alone or combination therapy including surgery (19 patients) and group B included patients on chemotherapy alone (19 patients). Clinical staging, modality of treatment, background diseases and demographic characteristics were compared. Patients with MALT lymphoma were excluded from the study. Patients in group-B were significantly older then patients in group-A (64.5 +/-8.9 vs. 57.4 +/-13.8, p=0.033) and had a shorter duration of symptoms (2.8 months +/-2 vs. 5.7 months +/-7, p=0.05). As for modalities of treatment, patients in group-A had better survival than group-B (112 months +/-45 vs. 79 months +/-46, p=0.03). Patients in stage 3 and 4, survival in group-A was better than in group-B (104 months +/-77 vs. 46 months +/-58, p< 0.05). Given the small amount and heterogeneous patients, we found a significant advantage to surgery or combination therapy over chemotherapy alone, especially in advanced clinical stage and survival was significantly higher in this group.
Aliza Zeidman , Gideon Y. Stein , Kanter Pazit , Amos H. Cohen , Fradin Zinaida and Edward Ram , 2007. Primary Gastric Non Malt Lymphoma: Comparison of Two Treatment Modalities and Survival in 44 Patients . Research Journal of Medical Sciences, 1: 174-177.