Authors : Ocal Sirmatel, Fatma Sirmatel, Fatma Nur Eris and Tekin Karsligil
Abstract: Epstein Barr Virus (EBV) infection often causes a triad of fever, sore throat and adenopathy, referred to as Infectious M ononucleosis. Gastrointestinal manifestations are frequently present but often unrecognized. The aim of this study is to present cases who admitted emergency service with acute cholestatic hepatitis and acute abdomen pain in the course of Ebstein-Barr Virus (EBV) infection. The five cases, two of whom were male and three female were between 14 and 51 years of age. In each of the cases, cholestatic hepatitis, mesenteric lymphadenomegaly and severe abdominal pain were observed. Also two of five patients showed thickening in the wall of the gallbladder (acalculosus hydropical gallbladder), ascites and multiple lymphadenomegaly in porta hepatis, paraaortocaval and mesenteric areas by abdominal ultrasonography. These clinical cases of acute cholestatic hepatitis resolves spontaneously in EBV infections with symptomatic treatment. Therefore these cases presented in order to draw attention to the fact that there may be different presentations in EBV infections. On the other hand, clinicians should be aware of co-occurence of acute cholestatic hepatitis during EBV infections. In such cases, radiology seriously helps to diagnosis, efficient radiological consultation and ultrasonic detection prevent drug overuse and invasive procedures.
Ocal Sirmatel, Fatma Sirmatel, Fatma Nur Eris and Tekin Karsligil, 2010. The Cases of Cholestatic Hepatitis in the Course of Atypical Epstein-Barr Virus Infection. Research Journal of Medical Sciences, 4: 136-141.