International Journal of Molecular Medicine and Advance Sciences

Year: 2010
Volume: 6
Issue: 4
Page No. 54 - 58

Clastogenic Studies on Hexaconazole: A Triazole Fungicide in Rats

Authors : P. Ravi Kumar, M. Kanniappan, L.N. Mathuram, S. Selvasubramanian and P. Sriram

References

Bohmont, B.L., 1996. The Standard Pesticide Users Guide. 4th Edn., Prentice Hall, New Jersey, USA., pp: 46-49.

Brusick, D.J., 1987. Principles of Genetic Toxicology. 2nd Edn., Plenum, New York and London.

Como, J.A. and W.E. Dismukes, 1994. Oral azole drugs as systemic antifungal therapy. N. Engl. J. Med., 330: 263-272.
PubMed  |  

Hiasa, Y., M. Ohshima, Y. Kitahori, T. Yuasa, T. Fujita and C. Iwata, 1982. Promoting effects of 3-amino-1,2,4-triazole on the development of thyroid tumors in rats treated with N-bis (2-hydroxypropyle) nitrosamine. Carcinogenesis, 3: 381-384.
PubMed  |  

Hoffman, G.R., 1996. Genetic Toxicology. In: Casarett and Doull`s Toxicology, Kalaassen, C.D. (Ed.). 5th Edn., McGraw-Hill Health Professions Division, New York, USA., pp: 2784.

Hosokawa, S., J. Nakamura, S. Ito, M. Murakami and M. Ineyama, 1993. Hormonal disregulation mechanism in the rat thyroid tumor induced by diniconazole. J. Toxicolog. Sci., 18: 57-67.
PubMed  |  

Kevekordes, S., T. Gebel, K. Pav, Edenharder, R. and H. Dunkelberg, 1996. Genotoxicity of selected pesticides in the mouse bone marrow micronucleus test and in the sister chromatic exchange test with human lymphocytes in vitro. Toxicol. Lett., 89: 35-42.
PubMed  |  

Laamanen, I., M. Sorsa, D. Bamford, U. Gripenberg and T. Meretoja, 1976. Mutagenicity and toxicity of amitrole. I. Drosophila tests. Mutat. Res., 40: 185-190.
CrossRef  |  

Mattioli, F., L. Robbiano, L. Fazzuoli and P. Baracchini, 1994. Studies on the mechanism of the carcinogenic activity of amitrole. Fundamen. Applied Toxicol., 23: 101-106.
PubMed  |  

Meretoza, T., U. Gripenberg, D. Bamford, I. Laamanen and M. Sorsa, 1976. Mutagenicity and toxicity of amitrole. II. Human lymphocyte culture tests. Mutat. Res., 40: 191-196.
PubMed  |  

Oldham, J.W., 1997. Genetic Toxicology. In: Comprehensive Toxicology, Sipes, I.G., C.A. McQueen and A.J. Gondolfi (Eds.). Vol. 2, Pergamon, Elsevier Science Ltd., Oxford, UK., pp: 133-144.

Preston, R.J., B.J. Dean, S. Galloway, H. Holden, A.F. Mcfee and M. Shelby, 1987. Mammalian in vivo cytogenetic assays analysis of chromosome aberrations in bone marrow cells. Mutat. Res./Genet. Toxicol., 189: 157-165.
CrossRef  |  PubMed  |  Direct Link  |  

Radman, M., P. Jeggo and R. Wagner, 1982. Chromosomal rearrangement and carcinogenesis. Mutat. Res., 98: 249-264.
PubMed  |  

Schmid, W., 1975. The micronucleus test. Mutat. Res., 31: 9-15.
CrossRef  |  PubMed  |  Direct Link  |  

Snedecor, G.W. and W.G. Cochran, 1968. Statistical Methods. 6th Edn., Oxford and IBH Publishing Company, New Delhi, India.

Sorsa, M. and U. Gripenberg, 1976. Organization of a mutagenicity test system combining instructive purposes: Testing for mutagenic effects of the herbicide amitrole. Mutat. Res., 38: 132-132.

Steinhoff, D., H. Weber, U. Mohr and K. Boehme, 1983. Evaluation of amitrole (aminotriazole) for potential carcinogenicity in orally dosed rats, mice and golden hamsters. Toxicol. Applied Pharmacol., 69: 161-169.
CrossRef  |  

Tomlin, C., 1995. The Pesticide Manual. 10th Edn., Crop Protection Publications, UK., pp: 562-563.

Tsuda, H., 1975. Studies on the effects of 3-amino-1,2,4-triazole in rat thyroids. Nagoya Shirtsu daigaku Igakkai Zasshi. J. Nagoya City Univ. Med. Assoc., 26: 78-94.

Uno, J., M.L. Shigematsu and T. Arai, 1982. Primary site of action of ketoconazole on Candida albicans. Antimicrobial Agents Chemotherapeutics, 21: 912-918.
PubMed  |  Direct Link  |  

Van den Bossche, H.D., D. Bellens, W. Cools and J. Gorrens et al., 1986. Cytochrome P450: Target for itraconazole. Drug Develop. Res., 8: 287-298.

WHO, 1974. World Health Organization International Agency for Research on Cancer. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. Vol. 7, IARC., Lyon, France.

Design and power by Medwell Web Development Team. © Medwell Publishing 2024 All Rights Reserved