Abstract: It is expected that the implementation of Electronic Health Record (EHRs) systems should be noted amongst others as one of the most exclusive strategies needed to improve the quality of care provided by nurses. Nonetheless, the under-utilization of the capabilities of the EHRs by the nurses have become of concern due to their technology-related personality in relation to accepting to use EHRs. For decades now, researchers and attendant empirical underpinnings have been concerned about people’s behaviours relating to adopting innovative IT and how those innovations are diffused. The critical nature of the above submission is noted. Conventionally, factors such as usefulness and ease of use have been used to examine technology adoption vis-a-vis the need to predict accepting technologies by individuals. Nevertheless, charting the above line-of-thought is noted to be plausibly problematic in that the determining factors of people’s perception on ease of use and usefulness in accepting a technology may not be properly understood and clarified. Consequently, further empirical endeavours aimed at suggesting improved interventions relating to people’s acceptance and eventual use of a technology is suggested and/or called for. Hence, this study further lengthens the unified theory of acceptance and use of technology (UTAUT2) so as to understand how technology acceptance and use in the health care setting with the incorporation of the TRI theory into UTAUT: optimism innovativeness, discomfort and insecurity.