Abstract: This study examines the relationship between information technology and organizational entrepreneurship in Yazd city's Saderat bank branches. In this regard, information technology based on the model by Chanoopas and other authors and organizational entrepreneurship based on the model by Leonidas and Vasilis has been used. The study population includes all the employees of the branches of Saderat bank of Yazd city that are equal to 800. The sample size using Krejcie and Morgan Table, determined to be 260. This study is applied in terms of purpose and is descriptive and correlational in terms of method. In order to determine the reliability of the questionnaires, Cronbach’s alpha coefficient, in order to determine the validity of the questionnaire, convergent and divergent validity method and in order to analyze the data, normality test and Pearson correlation coefficient and regression and variance were used. The results of this study showed that information technology has an impact on organizational entrepreneurship in Yazd Saderat bank branches.