Abstract: Innovation is as an important issue for individuals, institutions and overall, for all societies because of its relation with the flexibility and production. On the other hand, organizations reflect their resources in activities that have strategic direction and invest. The study of regression analysis shows that the entrepreneurial orientation and the orientation of technological is effective in the development of organizational innovation in Iran information technology organization based on its governance role to manage, support and organize the affairs related to security and technological development of information and their application in the country and rapid changes in this area. In other word, value of organizational innovation in the studied organization changes based on advantages of entrepreneurial orientation and technological orientation effectively. The study population was all the staff that their number is 400. The 196 of them were selected using random sampling method and Cochran formula. They responded to questionnaires of technological orientation and organizational innovation, entrepreneurial orientation. SPSS Software was used for data analysis.