Authors : T.A. Adeniyi, P.A. Adeonipekun and A.E. Omotayo
Abstract: In order to evaluate the medicinal value of notorious sedge weeds, three species: Cyperus esculentus, Cyperus rotundus and Mariscus alternifolius were investigated for their phytochemical constituents and antimicrobial properties. Preliminary qualitative phytochemical constituents and in vitro antimicrobial activities were evaluated against four fungi species Aspergillus niger, Aspergillus fumigatus, Penicillium chrysogenum and Candida albicans and three bacteria species Escherichia coli, Salmonella typhi and Staphylococcus aureus. Two solvents, water and ethanol were used to produce the extracts and screened for their antimicrobial activity. Antimicrobial activity evaluation of extracts against the pathogens was carried out at 100 mg mL-1 concentration by Disc Diffusion Method for fungi and Disc Diffusion and Agar Well Diffusion Methods for bacteria. Observed activities were related to standard antibiotics fulcin (antifungal), tetracycline (antibacterial) and Ciprofloxacin (antibacterial) which served as controls. Phytochemically, the plant extracts showed the presence of carbohydrates, flavonoids, ketose sugars, steroids, reducing sugars and tannins. The ethanolic extract of C. rotundus exhibited highest activity against A. niger, E. coli and S. aureus. No extract was active against C. albicans. From these findings, C. rotundus is a potential source of bioactive compounds for new drugs upon isolation and purification for treating infections caused by these pathogens.
T.A. Adeniyi, P.A. Adeonipekun and A.E. Omotayo, 2013. Investigating the Phytochemicals and Antimicrobial Properties of Three Sedge (Cyperaceae) Species. International Journal of Tropical Medicine, 8: 92-98.