Authors : Shu Jing-Ting, Li Hui-Fang, Zang Ying, Shan Yan-Ju, Xu Wen-Juan and Chen Kuan-Wei
Abstract: The Peroxisome Proliferators-activated receptor-γ Coactivator-1α (PGC-1α) was investigated as a candidate gene for meat quality and fatness traits in chicken because of its prominent role in muscle fiber specialization and adipogenesis. Variations of PGC-1α+646G/A may associate with chicken meat quality traits. The objective of the current research was to investigate the association of this single nucleotide polymorphisms in PGC-1α gene with meat quality traits in Recessive White chickens and Qingyuan Partridge chickens. Genotyping was performed by Polymerase Chain Reaction-Ligation Detection Reaction (PCR-LDR) Method. Marker-trait association analysis indicated that there were significant associations between G646A genotypes and the trait of water loss rate. Researchers putatively drew the conclusion that this SNP in PGC-1α gene could be used as the potential molecular marker for meat quality trait in chicken.
Shu Jing-Ting, Li Hui-Fang, Zang Ying, Shan Yan-Ju, Xu Wen-Juan and Chen Kuan-Wei, 2011. A Novel Method Based on Ligase Detection Reaction for PGC-1α G646A Gene Polymorphism and its Genetic Effect on Meat Quality in Chicken. Journal of Animal and Veterinary Advances, 10: 2921-2925.