Abstract: This research examined the relationship between mental health and job satisfaction among high school principals and teachers in Iran. It was hypothesized that global job satisfaction and its 5 components: Satisfaction with work, co-workers, pay, promotion and supervision have negative correlations with the 9 mental disorders: Somatization, obsessive-compulsive, interpersonal sensitivity, depression, anxiety, hostility, phobic anxiety, paranoid ideation and psychoticism. The JDI and the SCL-90-R were used to measure overall job satisfaction and its 5 components and the 9 mental disorders, respectively. The sample consisted of 828 subjects selected by a random method; 665 were teachers and 163 were principals. Results indicated that global job satisfaction and its 5 components have negative correlations with the 9 mental disorders at p<0.01 level of significance. Only 8 correlation coefficients out of 108 did not reach statistical significance at p<0.05 level. The multiple correlation coefficients of the 5 job satisfaction facets and the nine mental disorders have a range from 0.17-0.38 for teachers and from 0.34-0.45 for principals. All these multiple correlation coefficients were significant at p<0.01.