Abstract: Diabetes has become increasing in prevalence all over the world. Diabetes is associated with certain diseases such as Candidiasis. The objectives of the present study were to estimate the prevalence of Candida species in the oral cavity of diabetic and non-diabetic individuals at Al-Guraiat Governorate, Kingdom of Saudi Arabia and to evaluate the effects of smoking and denture wearing on the prevalence of Candida. A cross sectional study design was involved to collect data from all participants at within the time frame. Study sample included 100 patients with diabetes and 100 non-diabetics as a reference group. A questionnaire was constructed to collect data. Various oral sites were swabbed and cultured on Brain Heart Infusion (BHI) broth and inoculated on Sabourauds dextrose agar and incubated at 37°C for 48 h. Study findings showed that the prevalence of Candida among diabetics was 70% and among non-diabetic group was 30%. The prevalence of Candida among diabetic group was significantly associated with oral hygiene (p = 0.000), gingivitis (p = 0.004) and denture wearing (p = 0.002). Taken together, the results of the present study clearly showed that diabetic patients are more likely to develop Candida infection compared with non-diabetics. Candidiasis was significantly associated with oral hygiene, gingivitis and denture wearing.
Bader K. Alzarea, Mohd G. Sghaireen, Ibrahim Taher and Mazin Mohager, 2015. Prevalence of Oral Candidiasis in Diabetic Patients at Northern of Kingdom of Saudi Arabia. Research Journal of Biological Sciences, 10: 10-14.