Authors : Y.O. Adesiji , S.S. Taiwo , D.A. Adekanle , V.O. Oboro , S.A. Fayemiwo and O.O. Opaleye
Abstract: Although Bacterial Vaginosis (BV) is increasingly being recognized as a health problem among pregnant women, this entity has not been well studied in our environment. The aim of this study, is to determine the prevalence of BV among pregnant women attending the Antenatal Clinic (ANC) of our hospital and posible effects on pregnancy outcome. All pregnant women attending the ANC of Ladoke Akintola University Teaching Hospital (LAUTECH) between July 2004 and December 2005 with the exception of women with diabetics, pregnancy induced hypertension, sickle cell disease, human immunodeficiency virus infection, obstetric complications or women who have taken antibiotics 2 weeks prior to ANC visit, were prospectively studied. High vaginal swab was collected from each woman at the 1st or 2nd trimester of pregnancy and subjected to wet film microscopy and Gram reaction. BV was diagnosed using the clinical criteria recommended by Amsel et al and Gram stain morphology described by Spiegel. All the women were followed up till delivery to determine outcome of pregnancy. Of the total of 204 pregnant women studied (age range 20-40 years, mean age 28.941±4.214, median age 28.5years), 51 had BV, giving a prevalence of 25%; 48 had BV by both clinical criteria and Gram stain morphology, 2 had BV by clinical criteria alone while 1 had BV by Gram stain morphology alone. The overall agreement between the two methods is 94.1%. The age of women with BV ranged between 22 and 44 years (mean age 28.118±4.299 years). There was no significant difference in the mean age of women with BV and those without BV (p=0.3560). BV was commoner among primigravidae (27/51) than multigravidae (24/51) (p=0.0341). Twelve of 153 (7.84%) women without BV had pre-term deliveries while 9 of 51 (17.65%) with BV had pre-term deliveries (p=0.0614). Primigravidae with BV (6/9) did not significantly had more preterm deliveries than those without BV (3/12) (p=0.4857). The mean birth weight of 3.151±0.5562 kg among women with BV was also not significantly different from the mean birth weight of 3.074±0.4629 kg among women without BV (p=0.5707). Although the prevalence of BV is high among pregnant women in our environment, our study did not demonstrate any significant adverse effect on pregnancy outcome.
Y.O. Adesiji , S.S. Taiwo , D.A. Adekanle , V.O. Oboro , S.A. Fayemiwo and O.O. Opaleye , 2007. Bacteria Vaginosis and Pregnancy Outcome in Osogbo, Nigeria . Research Journal of Medical Sciences, 1: 195-198.