Authors : Gamal Enan, Sara Hamdy, Seham Abdel-Shafi and Abdul-Raouf Al-Mohammadi
Abstract: In this review, the characteristics, classification, pathogenesis and diagnosis of Streptococcus pyogenes (S. pyogenes) infections are discussed. In addition, a list of antibiotics and natural agents necessary to inhibit S. pyogenes are listed herein. S. pyogenes is a group A beta-hemolytic Streptococcus. It is a facultative anaerobe, non-motile, non-sporing, spherical or ovoidal cocci. Many virulence factors are produced by S. pyogenes and are responsible for its infections such as streptolysin O, streptolysin S, streptococcal pyogenic exotoxin A and exotoxin C, streptokinase, hyaluronidase and C5a peptidase. Pathogenic causes of S. pyogenes are pharyngitis, impetigo, sepsis, erysipelas, Cellulities, puerperal fever, scarlet fever, rheumatic fever, glomerulonephritis and toxic shock syndrome. Serology, culturing and microscopic examination of S. pyogenes are the most important ways of diagnosis. The recent ways to inhibit S. pyogenes by natural agents (honey, essential oils, plant extracts) are also discussed.
Gamal Enan, Sara Hamdy, Seham Abdel-Shafi and Abdul-Raouf Al-Mohammadi, 2016. Biological Characteristics and Inhibition by Both Natural Agents and Antibiotics of Streptococcus Pyogenes. Research Journal of Medical Sciences, 10: 573-586.