Authors : Long Jiang, Anchun Cheng, Mingshu Wang, Dekang Zhu, Renyong Jia and Xiaoyue Chen
Abstract: Duck Plague Virus (DPV) is a member of the Alphaherpesviridae subfamily and an important pathogen in domestic and wild ducks, geese, swans and other water fowl with migratory waterfowl contributing to spread between continents. VP22 is a structural protein assembled into the tegument compartment of the virion, highly conserved across the Alphaherpesviridae. The precise biological function performed by the VP22 tegument protein encoded by UL49 gene in the virus life cycle remains to be elucidated. In this report, researchers aimed at elucidating the subcellular localization of VP22 in DPV infected primary duck embryo fibroblasts the recombinant VP22 protein and VP22-GFP fusion protein in DEF cells. Transcription characteristics of UL49 gene was analyzed by RTFQ-PCR.
Long Jiang, Anchun Cheng, Mingshu Wang, Dekang Zhu, Renyong Jia and Xiaoyue Chen, 2012. Characterization of Duck Plague Virus Tegument Protein VP22. Veterinary Research, 5: 82-90.