Authors : N. Kataria, A.K. Kataria, N. Pandey, R. Maan, A. Joshi, L.N. Sankhla, M. Chaturvedi, R. Pachauri and P.K. Pilania
Abstract: An investigation was carried out in 1235 male and female goats of Marwari breed belonging to arid tracts in India to find out the role of serum magnesium as a biomarker of oxidative stress. The samples were collected during moderate and hot ambiences from apparently healthy animals and from the animals having gastrointestinal parasites, Peste des Petits Ruminants (PPR), mange and those affected by drought. The mean value recorded during moderate ambience was considered as control. The mean value of serum magnesium during hot ambience of animals having gastrointestinal parasites, PPR, mange and those affected by drought were significantly (p≤0.05) lower than control mean value. Minimum value was observed in drought affected animals. The control mean value of serum magnesium was 1.24±0.003 m mol L-1 and the lowest value in drought affected animals was 0.49±0.002 m mol L-1. Simultaneously, serum catalase was also determined in each case to assess oxidative stress because it is considered as a potent marker of oxidative stress. Significantly higher (p≤0.05) values of serum catalase in each case revealed the presence of oxidative stress in animals. A concomitant decrease in serum magnesium reflected towards its antioxidant property. It was concluded that oxidative stress resulted in lowering in the serum magnesium levels however, impact varied. Low serum magnesium in gastrointestinal parasitised, PPR, mange and drought affected animals could be the outcome of oxidative stress to the animals and therefore it can be opined that dietary deficiency of magnesium is not the only reason behind the low magnesium levels but oxidative stress mechanism also play pivotal role. Serum magnesium can be used effectively as one of the biomarkers to assess oxidative stress.
N. Kataria, A.K. Kataria, N. Pandey, R. Maan, A. Joshi, L.N. Sankhla, M. Chaturvedi, R. Pachauri and P.K. Pilania, 2012. Use of Serum Magnesium as a Biomarker of Oxidative Stress in Marwari Goat from Arid Tracts in India. Veterinary Research, 5: 91-96.