Authors : Mrigakshi Yadav, S.K. Rastogi, Satish Kumar and Malini Pant
Abstract: Monitoring anaesthetic depth allows recognizing the extent of physiological stress. Heart is the core organ directly influenced by stress while hematological and biochemical analysis allow quick and accurate diagnosis. This study aimed to evaluate stress on goats subjected to propofol and xylazine-ketamine anaesthesia electrocardiographically, hematologicaly, biochemicaly and by clinical parameters thereby suggesting a suitable anaesthetic for short term surgical interventions. Twelve healthy adult female crossbred goats, aged 2-4 years were randomly allocated to two groups according to the anaesthetics. Electrocardiography (ECG), Oxyhemoglobin (HbO2) saturation, Hematological (Hb concentration, PCV, TEC, TLC, DLC, MCV, MCH and MCHC), blood glucose and clinical parameters (rectal temperature, pulse and respiratory rates) were assessed. The results indicated that after propofol and xylazine-ketamine administration HbO2 decreased (within normal physiological limits after xylazine-ketamine administration), all ECG parameters increased except QRS interval (no change). During propofol anaesthesia rectal temperature, respiratory rate and hematological parameters (except lymphocyte count) decreased while blood glucose concentration and pulse rate increased. During xylazine-ketamine anaesthesia, similar observations were recorded except that pulse rate decreased and MCHC non-significantly increased. Propofol produced favorable effects on cardiovascular system, rectal temperature and pulse rate whereas, xylazine-ketamine exerted more effective anaesthetic effects on respiratory system, blood glucose concentration and hematology suggesting it to be a safer and better choice over propofol for short period anaesthetic requirements in goats. Therefore, it could be suggested for further investigations in clinical conditions.
Mrigakshi Yadav, S.K. Rastogi, Satish Kumar and Malini Pant, 2017. Electrocardiological, Hemato-Biochemical and Clinical Evaluation of Parentral Anaesthesia in Goats. Veterinary Research, 10: 21-27.