Authors : Mehmet Ozsan and Zafer Durngu
Abstract: Puberty is a period in which dramatic changes occur in human life. This study was conducted to determine the effects of nandrolone and testosteron on some blood parameters in rabbits. In this study 60 days old, healthy, weighing nearly each other, 30 New Zealand rabbits were used. Animals were separated in 2 main groups as control (7%; 8&) and experimental (7%; 8&). The 10 mg kg–1 nandrolone and 10 mg kg–1 testosterone was injected subcutaneously to experimental group 1 day of per week. The application was continued for 90 days. In the plasma samples taken on the 45 and 90th days of the study, total cholesterol, HDL cholesterol and LDL cholesterol concentrations were determined. LDL cholesterol levels increased both in female and male experimental groups in each sampling time (45 and 90th days) and total cholesterol levels increased only 90th days (p<0.05). On 45th day, HDL cholesterol level was tending to decrease in female experimental group but this decrease was significantly (p<0.05) in male experimental group. Reduction in the level of HDL was also significantly in both experimental groups on 90th day (p<0.05). Consequently, the findings received from the study which resulted in the side effects of nandrolon+testosterone application regarding the parameters, seems important for that it reveals the effects of AAS in puberty.
Mehmet Ozsan and Zafer Durngu, 2018. The Effect of Nandrolone and Testosterone on Cholesterol in Rabbits During Puberty. Veterinary Research, 11: 20-23.