Journal of Animal and Veterinary Advances

Year: 2012
Volume: 11
Issue: 10
Page No. 1588 - 1594

Effect of PPARα’s over Expression on the Type 2 Diabetic Rat Cardiomyocytes

Authors : Liang ZiWen, Wu QiNan, Tang QiuShan, Chen Bing, Wu Ping, Gao Yuan and Xiao Qian

References

Aussedat, J., A. Ray and L. Kay, 2006. Improvement of long term preservation of isolated arrested heart: Beneficial effect of ant ischemic agent trimetazidine. J. Cardiovasc. Pharmacol., 21: 128-128.

Boudina, S. and E.D. Abel, 2007. Diabetic cardiomyopathy revisited. Circulation, 115: 3213-3223.
PubMed  |  Direct Link  |  

Carley, A.N. and D.L. Severson, 2005. Fatty acid metabolism is enhanced in type 2 diabetic hearts. Biochim. Biophys. Acta., 1734: 112-126.
PubMed  |  

Chen, X.P., W.Y. Yang, S. Bu, J.Z. Xiao, X.L. Liu, N. Wang and W.H. Zhao, 2004. Effects of rosiglitazone and metformin on insulin resistance in high-fat diet rats. Zhonghua Nei Ke Xue Za Zhi, 43: 280-283.
PubMed  |  

Dyntar, D., M. Eppenberger-Eberhardt, K. Maedler, M. Pruschy, H.M. Eppenberger, G.A. Spinas and M.Y. Donath, 2001. Glucose and palmitic acid induce degeneration of myofibrils and modulate apoptosis in rat adult cardiomyocytes. Diabetes, 50: 2105-2113.
CrossRef  |  Direct Link  |  

Fang, Z.Y., J.B. Prins and T.H. Marwick, 2004. Diabetic cardiomyopathy: Evidence, mechanisms and therapeutic implications. Endocr. Rev., 25: 543-567.
PubMed  |  

Farhangkhoee, H., Z.A. Khan, S. Chen and S. Chakrabarti, 2006. Differential effects of curcumin on vasoactive factors in the diabetic rat heart. Nutrit. Metab., 10.1186/1743-7075-3-27

Finck, B.N., X. Han, M. Courtois, F. Aimond and J.M. Nerbonne et al., 2003. A critical role for PPAR α-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: Modulation by dietary fat content. Proc. Natl. Acad. Sci., 100: 1226-1231.
CrossRef  |  PubMed  |  Direct Link  |  

How, O.J., E. Aasum, D.L. Severson, W.Y. Chan, M.F. Essop and T.S. Larsen, 2006. Increased myocardial oxygen consumption reduces cardiac efficiency in diabetic mice. Diabetes, 55: 466-473.
PubMed  |  

Lefebvre, P., G. Chinetti, J.C. Fruchart and B. Staels, 2006. Sorting out the roles of PPARα in energy metabolism and vascular homeostasis. J. Clin. Invest., 116: 571-580.
Direct Link  |  

Matsuzawa, Y., 2006. The metabolic syndrome and adipocytokines. FEBS Lett., 580: 2917-2921.
PubMed  |  

Poornima, I.G., P. Parikh and R.P. Shannon, 2006. Diabetic cardiomyopathy: The search for a unifying hypothesis. Circ. Res., 98: 596-605.
PubMed  |  Direct Link  |  

Rosano, G.M., C. Vitale, B. Sposato, G. Mercuro and M. Fini, 2003. Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: A double-blind placebo-controlled study. Cardiovasc. Diabetol., 2: 16-16.
CrossRef  |  PubMed  |  

Tabbi-Anneni, I., C. Helies-Toussaint, D. Morin, A. Bescond-Jacquet, A. Lucien and A. Grynberg, 2003. Prevention of heart failure in rats by trimetazidine treatment: A consequence of accelerated phospholipid turnover? J. Pharmacol. Exp. Ther. Fast Forward, 304: 1003-1009.
PubMed  |  

Young, M.E., F.A. Laws, G.W. Goodwin and H. Taegtmeyer, 2001. Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart. J. Biol. Chem., 276: 44390-44395.
Direct Link  |  

Design and power by Medwell Web Development Team. © Medwell Publishing 2024 All Rights Reserved