References

Abraham, E.J., C.A. Leech, J.C. Lin, H. Zulewski and J.F. Habener, 2002. Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells. Endocrinology, 143: 3152-3161.
CrossRef  |  PubMed  |  

Bar-Nur, O., H.A. Russ, S. Efrat and N. Benvenisty, 2011. Epigenetic memory and preferential lineage-specific differentiation in induced pluripotent stem cells derived from human pancreatic islet beta cells. Cell Stem Cell, 9: 17-23.
CrossRef  |  

Bonner-Weir, S., 2000. Perspective: Postnatal pancreatic β cell growth. Endocrinology, 141: 1926-1929.
CrossRef  |  

Bonner-Weir, S., M. Taneja, G.C. Weir, K. Tatarkiewicz, K.H. Song, A. Sharma and J.J. O'Neill, 2000. In vitro cultivation of human islets from expanded ductal tissue. Proc. Natl. Acad. Sci. USA., 97: 7999-8004.
CrossRef  |  

Butler, A.E., A. Huang, P.N. Rao, A. Bhushan, W.J. Hogan, R.A. Rizza and P.C. Butler, 2007. Hematopoietic stem cells derived from adult donors are not a source of pancreatic beta-cells in adult nondiabetic humans. Diabetes, 56: 1810-1816.
PubMed  |  

Danner, S., J. Kajahn, C. Geismann, E. Klink and C. Kruse, 2007. Derivation of oocyte-like cells from a clonal pancreatic stem cell line. Mol. Human Reprod., 13: 11-20.
CrossRef  |  

Davani, B., L. Ikonomou, B.M. Raaka, E. Geras-Raaka, R.A. Morton, B. Marcus-Samuels and M.C. Gershengorn, 2007. Human Islet‐derived precursor cells are mesenchymal stromal cells that differentiate and mature to hormone‐expressing cells in vivo. Stem Cells, 25: 3215-3222.
CrossRef  |  

Dominguez-Bendala, J. and C. Ricordi, 2012. Present and future cell therapies for pancreatic beta cell replenishment. World J. Gastroenterol., 18: 6876-6884.
CrossRef  |  PubMed  |  Direct Link  |  

Dominguez-Bendala, J., 2009. Pancreatic Stem Cells. 1st Edn., Humana Press, New York, Pages: 254.

Eberhardt, M., P. Salmon, M.A. von Mach, J.G. Hengstler and M. Brulport et al., 2006. Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets. Biochem. Biophys. Res. Commun., 345: 1167-1176.
CrossRef  |  

Ferber, S., A. Halkin, H. Cohen, I. Ber and Y. Einav et al., 2000. Pancreatic and duodenal homeobox gene 1 induces expression of insulin genes in liver and ameliorates streptozotocin-induced hyperglycemia. Nat. Med., 6: 568-572.
CrossRef  |  

Gershengorn, M.C., A.A. Hardikar, C. Wei, E. Geras-Raaka, B. Marcus-Samuels and B.M. Raaka, 2004. Epithelial-to-mesenchymal transition generates proliferative human islet precursor cells. Science, 306: 2261-2264.
CrossRef  |  

Hui, R., C. Wright and R. Perfetti, 2001. Glucagon-like peptide 1 induces differentiation of islet duodenal homeobox-1 positive pancreatic ductal cells into insulin-secretion cells. Diabetes, 50: 785-796.
CrossRef  |  PubMed  |  

Jiang, J., M. Au, K. Lu, A. Eshpeter, G. Korbutt, G. Fisk and A.S. Majumdar, 2007. Generation of insulin‐producing islet‐like clusters from human embryonic stem cells. Stem Cells, 25: 1940-1953.
CrossRef  |  

Jonsson, J., L. Carlsson, T. Edlund and H. Edlund, 1994. Insulin-promoter-factor 1 is required for pancreas development in mice. Nature, 371: 606-609.
CrossRef  |  

Kadam, S., V. Govindasamy and R. Bhonde, 2012. Generation of Functional Islets from Human Umbilical Cord and Placenta Derived Mesenchymal Stem Cells. In: Somatic Stem Cells, Singh, S.R. (Ed.). Humana Press, India, pp: 291-313.

Kilimnik, G., J. Jo, V. Periwal, M.C. Zielinski and M. Hara, 2012. Quantification of islet size and architecture. Islets, 4: 167-172.

Korbutt, G.S., J.F. Elliott, Z. Ao, D.K. Smith, G.L. Warnock and R.V. Rajotte, 1996. Large scale isolation, growth and function of porcine neonatal islet cells. J. Clin. Invest., 97: 2119-2129.
CrossRef  |  

Lee, S.H., E. Hao, A.Y. Savinov, I. Geron, A.Y. Strongin and P. Itkin-Ansari, 2009. Human β-cell precursors mature into functional insulin-producing cells in an immunoisolation device: Implications for diabetes cell therapies. Transplantation, 87: 983-991.
PubMed  |  

Li, Y., L.J. Zhao, F.Z. Xia, Y.X. Li and Y.L. Lu, 2012. Transdifferentiation of hepatic oval cells into pancreatic islet β-cells. Front Biosci. (Landmark Ed.), 17: 2391-2395.
PubMed  |  

Lin, H.T., S.H. Chiou, C.L. Kao, Y.M. Shyr and C.J. Hsu et al., 2006. Characterization of pancreatic stem cells derived from adult human pancreas ducts by fluorescence activated cell sorting. World J. Gastroenterol., 12: 4529-4535.
PubMed  |  

Madsen, O.D., 2007. Pancreas phylogeny and ontogeny in relation to a pancreatic stem cell. Comptes Rendus Biol., 330: 534-537.
CrossRef  |  

Marappagounder, D., I. Somasundaram, S. Dorairaj and R.J. Sankaran, 2013. Differentiation of mesenchymal stem cells derived from human bone marrow and subcutaneous adipose tissue into pancreatic islet-like clusters in vitro. Cell. Mol. Biol. Lett., 18: 75-88.
CrossRef  |  

Merani, S. and A.M. Shapiro, 2006. Current status of pancreatic islet transplantation. Clin. Sci., 110: 611-625.
CrossRef  |  

Offield, M.F., T.L Jetton., P.A. Labosky, M. Ray and R.W. Stein et al., 1996. PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development, 122: 983-995.
Direct Link  |  

Ouziel-Yahalom, L., M. Zalzman, L. Anker-Kitai, S. Knoller and Y. Bar et al., 2006. Expansion and redifferentiation of adult human pancreatic islet cells. Biochem. Biophys. Res. Commun., 341: 291-298.
CrossRef  |  PubMed  |  

Paredes, B., A. Santana, M.I. Arribas, N. Vicente-Salar and P.N. de Aza et al., 2011. Phenotypic differences during the osteogenic differentiation of single cell-derived clones isolated from human lipoaspirates. J. Tissue Eng. Regener. Med., 5: 589-599.
CrossRef  |  

Prabakar, K.R., J. Dominguez-Bendala, R.D. Molano, A. Pileggi, S. Villate, C. Ricordi and L. Inverardi, 2012. Generation of glucose-responsive, insulin-producing cells from human umbilical cord blood-derived mesenchymal stem cells. Cell Transplant., 21: 1321-1339.
CrossRef  |  

Seeberger, K.L., J.M. Dufour, A.M.J. Shapiro, J.R. Lakey, R.V. Rajotte and G.S. Korbutt, 2006. Expansion of mesenchymal stem cells from human pancreatic ductal epithelium. Lab. Invest., 86: 141-153.
CrossRef  |  

Sharma, A., D.H. Zangen, P. Reitz, M. Taneja and M.E. Lissauer, 1999. The homeodomain protein IDX-1 increases after an early burst of proliferation during pancreatic regeneration. Diabetes, 48: 507-513.
PubMed  |  

Smukler, S.R., M.E. Arntfield, R. Razavi, G. Bikopoulos and P. Karpowicz et al., 2011. The adult mouse and human pancreas contain rare multipotent stem cells that express insulin. Cell Stem Cell, 8: 281-293.
CrossRef  |  

Stoffers, D.A., M.K. Thomas and J.F. Habener, 1997. Homeodomain protein IDX-1: A master regulator of pancreas development and insulin gene expression. Trends Endocrinol. Metab., 8: 145-151.
CrossRef  |  

Zhou, Q., J. Brown, A. Kanarek, J. Rajagopal and D.A. Melton, 2008. In vivo reprogramming of adult pancreatic exocrine cells to β-cells. Nature, 455: 627-632.
CrossRef  |  

Zuk, P.A., M. Zhu, P. Ashjian, D.A. De Ugarte and J.I. Huang et al., 2002. Human adipose tissue is a source of multipotent stem cells. Mol. Biol. Cell, 13: 4279-4295.
CrossRef  |  PubMed  |  Direct Link  |  

Zulewski, H., E.J. Abraham, M.J. Gerlach, P.B. Daniel and W. Moritz et al., 2001. Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine and hepatic phenotypes. Diabetes, 50: 521-533.
PubMed  |